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JUL/AUG 2013  

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Microscopic mouse hat

A miniature fluorescence microscope originally developed at Stanford University and used for neuroscienctific research on mice in 2011, was able to record neurons firing simultaneously in bands of up to 30 neurons while the mice were moving. The neuron pattern—something never before observed because it only appears when mice are actively moving—is shown in the video below.

The microscope, which weighs less than 2g, is attached to the skull of a mouse and worn like a hat (see image below video).

Microscopic mouse hat
Image courtesy Inscopix Inc.

In 2012, the researchers formed Inscopix Inc., Palo Alto, Calif., to commercialize the microscope system, now known as nVista HD. The system comes with data acquisition hardware and software. For more information about the technology, visit www.inscopix.com.